Calculus Capital

Calculus Capital Calculus Capital is one of the UK's longest-running venture capital managers, with ~£170M across EIS and VCT funds. Founded in 1999 by John Glencross and Susan McDonald, Calculus pioneered the UK's first approved EIS fund and has since backed over 60 companies across technology, life sciences, and creative industries. Their sweet spot is Series A investments of £1M–5M into UK-based startups. The portfolio has a strong biotech and life sciences pocket. companies like Ensilitech