Astera Institute

Astera Institute Astera Institute is not a traditional VC but rather one of the most significant science philanthropy organizations of the current era. Founded by Jed McCaleb (co-founder of Ripple and Stellar), it holds over $2 billion in assets dedicated to high-risk transformational science across longevity, AGI, metascience, and frontier engineering. The scale of commitment is extraordinary: $600M+ pledged to neuroscience research alone, led by Dr. Doris Tsao over a decade-long program. Aster